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MenaQ7 study on healthy children

Researchers concluded that supplementation with MenaQ7 vitamin K2 increases circulating concentrations of MK-7 and increases osteocalcin activation.


The incidence of forearm fractures in children peaks around the time of the pubertal growth spurt, possibly because physical activity increases at the same time that there is less cortical bone mass due to the increased calcium demand during skeletal growth. A population-based study in Minnesota examined whether there has been a change in the incidence of forearm fractures in children in recent years by reviewing data on forearm fractures during 4 time periods: 1969-1971, 1979-1981, 1989-1991, and 1999-2001. The results showed that annual incidence rates of forearm fractures per 100,000 increased from 263.3 in 1969-1971 to 322.3 in 1979-1981, and to 399.8 in 1989-1991 before leveling off at 372.9 in 1999-2001. Age-adjusted incidence rates per 100,000 were 32% greater among male residents in 1999-2001 compared with 1969-1971 (P =0.01), and 56% greater among female residents in the same time periods (P < 0.001).







In comparing the previous data on the decreased intake of vitamin K from the 1950s to the 1990s (a 40-year period) with the data from the Minnesota study showing an increase in forearm fractures over a similar 30-year period, it is interesting to note the graphic correlation between the two sets of data; namely, as vitamin K intake in children decreased, forearm fractures in children increased.

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